Automated cultivation and processing of human cells on a novel chip system (Lab-on-a-Chip) - Masterthesis

Kennziffer IPA-2020-227

Several institutes of the Fraunhofer Gesellschaft are working together on an innovative lab-on-a-chip system for the human biology. Lab-on-a-chip systems are regarded as important key components to replace animal experiments in the pharmaceutical industry or to investigate the complex interaction between different cell types. In order to make this technology economically relevant, however, it requires robust processes and high production figures.
The Department of Laboratory Automation and Bioproduction Technology at Fraunhofer IPA is responsible for the automation of the chip and the interface of the microfluidic system to classical automation technology. Within this project, the handling of the cells on a liquid handling robot (pipetting robot) must be established and investigated.
Your tasks include:

• Establishment of aseptic cell handling with liquid handling robots (e.g. induction of cells, transfer and sterilisation)
• Establishment of work protocols for various liquid handling robots
• Routine cultivation of human cells with determination of live cell counts, as well as the preparation of substrate and metabolite concentration sequences
• Research and (independent) design of experiments
• Detailed documentation and evaluation of the results according to common scientific practice
  

Was Sie mitbringen

• Motivation, creativity and independent work
• Study of biology, medical technology, biotechnology or similar disciplines
• Experience and knowledge in cell culture
• Practical experience in dealing with human cells and in programming is an additional advantage
• Technical understanding and interest in interdisciplinary and innovative topics
• Good knowledge of German and/or English (written and spoken)

Was Sie erwarten können
What to expect:

• Collaboration in an interdisciplinary team on an innovative research project with industrial relevance
• Scientific work on a practice-relevant, highly topical and exciting subject area
• Flexible working hours and an excellent working atmosphere

(keine Angaben)

Fraunhofer ist die größte Organisation für anwendungsorientierte Forschung in Europa. Unsere Forschungsfelder richten sich nach den Bedürfnissen der Menschen: Gesundheit, Sicherheit, Kommunikation, Mobilität, Energie und Umwelt. Wir sind kreativ, wir gestalten Technik, wir entwerfen Produkte, wir verbessern Verfahren, wir eröffnen neue Wege.

Fraunhofer-Institut für Produktionstechnik und Automatisierung
Stuttgart

http://www.ipa.fraunhofer.de

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