Fraunhofer-Institut für Produktionstechnik und Automatisierung
The Biomedical Optics Group at Fraunhofer PAMB and the Computer Assisted Interventions (CAI) group at DKFZ collaborate to develop novel camera-based techniques to non-invasively quantify the amount of hemoglobin in tissue and its oxygen saturation, increasing the clinical value of various diagnostic imaging methods.
Fraunhofer PAMB is a project group of the Fraunhofer IPA active in the R&D of automation technologies for biomedical applications. The Biomedical Optics group develops novel real-time fluorescence imaging systems.
The CAI group investigates the automated analysis of medical images for the purpose of disease characterization and computer-aided diagnosis. It is part of DKFZ, the largest biomedical research institute in Germany.
Design and validation of tissue-mimicking phantoms for optical measurement of hemoglobin concentration and oxygen saturation - Thesis (Studien-/Abschlussarbeit)
What you can expect from us:
We offer friendly working environment in an international team, hands-on experience with state-of-the-art technologies. We encourage and support pursuing your own ideas. A related HiWi position is available in the Biomedical Optics lab at Fraunhofer PAMB. The development and measurement of the phantoms will be supervised by PAMB, while the data interpretation and evaluation will be overseen by DKFZ.
What we expect from you:
We are searching for an outstanding and highly motivated student (field of study: physics, chemistry, medical engineering, biotechnology or related) with deep understanding of the nature of light and optical properties as well as experience working in a laboratory environment. We look for someone able to work independently, with good attention to detail, a high standard for quality and scientific curiosity.
The scope of the thesis work is to develop and validate tissue-mimicking phantoms on which the new technologies can be tested. The objective is to match the literature values of optical properties of tissue, focusing on brain tissue at first, while reliably varying the hemoglobin content and oxygen saturation. Several liquid and solid phantoms representing homogeneous and non-homogeneous distributions of hemoglobin and oxygen should be built and validated. The primary focus of validation is the hemoglobin concentration and oxygen saturation, as well as the bulk spectral characteristics of the phantoms. According to progress and interest, the project can be expanded to include Monte Carlo simulations or assessment and analysis of the phantom images acquired with a novel multi-spectral imaging system developed at Fraunhofer PAMB.
Fragen zu dieser Position beantwortet gerne:
Frau Nina Warth
Tel.: 0711 970 1130
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