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The Max Planck Unit for the Science of Pathogens headed by its director Prof. Emmanuelle Charpentier is seeking a full time scientist position to head a Research Platform for Proteomics.
The Max Planck Unit for the Science of Pathogens is an international research institute currently being established, whose research focuses on
basic biological principles in bacterial pathogens (https://www.emmanuelle-charpentier-lab.org).
We are particular interested in genetic and biochemical mechanisms of regulation by RNAs and proteins in bacterial pathogens causing diseases in humans, and in viruses
of these pathogens. The overall aims of the Unit`s research are to gain a better understanding of the molecular and cellular mechanisms that control and regulate bacterial
We are seeking a highly motivated and talented scientist with excellent skills and knowledge in mass spectrometry to establish and direct a state-of-the-art
Proteomics Research Platform, including personnel. The successful candidate will be expected to develop, innovate and implement new advances in technology
and bioinformatics relevant to proteomics to support and propel research forward at our Unit. The successful candidate’s tasks include general management
of the research platform, instrument maintenance, routine analyses and method development, as well as all data acquisition and interpretation. The Unit also
hosts a Bioinformatics Research Platform that will provide support for data analysis. In addition, resources will be available to follow independent research projects.
The successful applicant should have experience in:
Global proteome profiling by Data-Dependent and Data-Independent Acquisition (DIA) mass-spectrometry
Relative quantification of proteins and proteomes by stable isotope labeling/proteome-wide quantification techniques, including label-free, SILAC, stable isotope dimethyl labeling, iTRAQ and/ or TMT
In vivo proteomics of bacterial infections
Structural proteomics (cross-linking)
The successful candidate will join an international and collaborative team in an outstanding and competitive scientific environment.
We are seeking highly qualified scientists with an excellent research track record. The successful candidate is expected to set up and
maintain the scientific and technical expertise of the research platform, support research at the highest standards, oversee the work
of younger scientists (PhD, master and undergraduate students), and contribute actively to collaborative and complementary research across the Unit.
The candidate’s qualification should include:
PhD in Biochemistry, Chemistry, Genetics, Immunology, Microbiology and/or Molecular Biology
Hands-on experience with LC-MS/MS, quantification methods and bioinformatics
A proven record of successful publications in highly respected international scientific journals
A successful post-doctoral experience
Fluent in English language
Experience working abroad is considered as an advantage
Friendly disposition, confident and responsible work ethics
Working independently and as part of an international team
Self-motivated and enthusiastic to work in a competitive, dynamic, stimulating and interacting international scientific environment focusing on basic biological research
The position is initially for five years with the possibility of becoming a permanent position after positive evaluation. The payment level is based on the
German state public service salary scale (up to E15, TVöD-Bund) according to the training, qualifications and professional experience. The benefits
correspond to the regulations of the public service. The position is available at the earliest possible date. The Max Planck Society is committed to employing
more handicapped individuals and especially encourages them to apply. Furthermore, the Max Planck Society seeks to increase the number of women in those areas
where they are underrepresented and therefore explicitly encouraged women to apply.