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The European Translational Oncology Prevention and Screening Institute (EUTOPS) is a new research institute at the University of Innsbruck, supported by the Land Tirol and led by Prof Martin Widschwendter, who also holds a professorship at University College London and a guest professorship at the Karolinska Institutet in Stockholm. Our research focus is to identify and validate epigenetic signatures for individualised prevention, risk prediction, and early detection of cancer in line with the principles of P4 medicine (predictive, preventive, personalised and participatory). Within this context, our work focuses on DNA methylation-based risk prediction and monitoring of cancer preventive measures in a translational setting, applying high throughput methodologies in international clinical trials and population-based samples.
We are currently establishing a new high-throughput epigenetics and genetics laboratory and are therefore looking for two laboratory technicians.
The University of Innsbruck’s newly established translational epigenetics laboratory is located in close proximity to a large pathology/cytology/molecular laboratory and sited 50 minutes west of Innsbruck close to several famous ski resorts (e.g. St. Anton, Lech, Pitztal, and Sölden) allowing for ample leisure activities in winter and summer yet within a short distance of major European cities such as Innsbruck, Munich, Zurich, and Verona.
The role and what will make you an ideal candidate
You will join an interdisciplinary, international, and highly motivated team with expertise in epigenetics, clinical research, biostatistics and oncology. You will be responsible for the day-to-day operation of our high-throughput epigenetics (and genetics) analysis pipelines and sample processing as well as laboratory maintenance and regular communication with the team.
This role will be an excellent opportunity for a scientist or laboratory technician with expertise in high-throughput technologies. We highly value team members capable of working independently with a sense of self-initiative and “can do” attitude.
Your tasks and responsibilities:
Operation of the “wet lab” part of our new high-throughput laboratory, including laboratory processes and related administrative and safety tasks, such as (but not limited to) the following:
General maintenance of the lab.
Operation of our high-throughput pipeline:
DNA extraction and modification (bisulfite conversion, restriction, etc.),
Array (mainly IlluminaEPIC array),
RT-PCR (e.g., MethyLight).
Regular diligent processing of clinical samples.
Troubleshooting and optimisation of above workflows.
Ensuring compliance with all internal and external policies as well as health and safety guidelines.
Regular communication with other members of the institute, providing updates on progress, areas of improvement or risks.
Prioritise tasks in line with short- and long-term needs of the research group.
Your profile: Essential
Bachelor’s degree in biology, biotechnology, biomedical analytics or similar, or demonstrated equivalent experience (master’s degree preferred).
Minimum of two years of laboratory experience.
Excellent molecular biology skills.
Diligent, independent and reliable work ethics with attention to detail for both administrative and laboratory tasks.
Excellent organisation and communication skills.
Perseverance to diligently process large sample numbers.
Good English communication skills (verbal and written).
Advanced degree in the above subjects.
Expertise and skills in (epigenetic and genetic) molecular biology techniques, including array technology, MethyLight analysis or next generation sequencing.
Experience with laboratory information management systems (LIMS) and working under ISO accreditation.
Experience with high-throughput pipelines and automation, e.g. liquid handling robots.
Knowledge of German, or willingness to learn.
This project staff (ProjektmitarbeiterIn) role is open-ended and attracts a minimum gross salary of € 2.929,00/month (14x) at 40 h a week, with salary commensurate with experience. In addition to this, the University of Innsbruck offers many attractive add-on benefits to its employees and staff (https://www.uibk.ac.at/universitaet/zusatzleistungen/index.html.en).
The University of Innsbruck is striving for an increased percentage of female employees and is therefore actively encouraging applications from qualified women, in particular for scientific positions. In case of underrepresentation, females of equivalent qualifications will be preferentially employed.