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Assistant Professor Sebastian Deindl
The Deindl laboratory (www.deindl-lab.com), located in the beautiful Stockholm area, is looking for two postdocs to work on an ERC-funded project investigating chromatin-associated complexes using state-of-the-art single-molecule fluorescence imaging approaches (position 1) or an integrated structural biology approach that combines cryo-EM, crystallography, and crosslinking-mass spectrometry (position 2).

Postdoc positions in Integrated Structural Biology and Single-Molecule Biophysics of chromatin-associated complexes

The Deindl lab (www.deindl-lab.com) is an international and ambitious research team that provides a stimulating and friendly environment for scientists with a genuine interest in tackling important biological questions. We have recently been awarded an ERC starting grant to investigate the molecular mechanisms of protein machines using a highly multidisciplinary approach that combines state-of-the-art single-molecule fluorescence imaging (see for example, Deindl et al., Cell 2013 or Hwang*, Deindl*, et al., Nature 2014) with a range of biophysical, structural, and biochemical techniques. 


Position 1: We are seeking a highly motivated postdoctoral researcher to carry out biophysical studies into the mechanisms of chromatin-associated complexes using single-molecule imaging approaches along with complementary biophysical and biochemical techniques. Several exciting projects are available and can be tailored to individual interests and expertise. The researcher will benefit from custom-built state-of-the-art single-molecule FRET microscopes, excellent resources, infrastructure, and support as well as collaborators who are international leaders in their fields.

Apply here: http://www.uu.se/en/about-uu/join-us/details/?positionId=117821


Position 2: We are seeking a highly motivated postdoctoral researcher to investigate the mechanisms and regulation of chromatin-associated complexes using an integrated structural biology approach that combines cryo-EM, crystallography, and crosslinking-mass spectrometry. The researcher will benefit from access to state-of-the-art facilities, infrastructure, resources and support for all these technologies, as well as collaborators who are international leaders in their fields. In particular, we have access to the SciLifeLab cryo-EM facility in Stockholm with state-of-the-art cryo-EM equipment, including Titan Krios and Talos Arctica armed with the latest generation direct electron detectors and a modern computational infrastructure. Cryo-EM work will be carried out in collaboration with Alexey Amunts' laboratory. 

Apply here:  http://www.uu.se/en/about-uu/join-us/details/?positionId=117851

Preferred Expertise/Qualifications

Applicants should possess a PhD in the life sciences, biophysics or physics, bioengineering, physical chemistry, or a related discipline. The ability to work in a team, good organizational skills as well as initiative, flexibility and good learning ability are required.

Position 1: A strong background in single-molecule biophysics or advanced fluorescence microscopy would be advantageous but is not strictly required, as well as prior experience with wet-lab biochemistry.

Position 2: A background in cryo-electron microscopy or X-ray crystallography, documented by at least one peer-reviewed first-author publication is strictly required. 

Bewerbungsfrist: 20.12.2016

Assistant Professor Sebastian Deindl
Husargatan 3
75237 Uppsala (Stockholm area)
E-Mail: sebastian.deindl@icm.uu.se


Bewerbungsschluss: 20.12.2016

Bewerbungsschluss: 20.12.2016 Erschienen auf ZEIT ONLINE am 18.11.2016
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