Your tasks:
The successful candidate will work on a project on innate immune training. More specifically, we have recently described that the alarmin heme induces persisting adaptations of myelopoiesis altering the host response to and disease course of polymicrobial sepsis. For further information, please read here:
PNAS, Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme. This research project is following these findings and the researcher will investigate prevailing phenotypes and the underlying metabolic regulatof heme-induced innate immune training. The project encompasses
in vivo and
in vitro infections, immunology techniques, such as bone marrow transplantations, and conventional molecular biology.
We expect:
- PhD degree in immunology, biology, biochemistry, or related life sciences
- Desirable methodological skills: background and expertise in molecular biology, biochemistry, cell biology, immunology and/or microbiology, animal models
- Excellent communication skills and team-oriented working attitude
- Outstanding track record of planning, performing, and publishing original research
- Fluency in English
We offer:
- An interesting, interdisciplinary project in the field of infection biology / immunology / host microbe interaction with a long-term work contract
- State-of-the-art equipment at an internationally renowned research institute in close cooperation with the Jena University Hospital
- Support for further qualifications at the institute and by attending courses offered by the Graduate Academy of the Friedrich Schiller University Jena
- Possibility for habilitation according to the requirements of the Medical Faculty of the Friedrich-Schiller University of Jena
- A salary which is paid according to German TV-L (salary agreement for public service employees)
- A family-friendly working environment with a variety of offers for families
The successful candidate will be hosted in the research group
Translational Infection Medicine of
Prof. Dr. Sebastian Weis. The Leibniz-HKI is embedded in the outstanding scientific environment of the Beutenberg Campus providing state-of-the-art research facilities and a highly integrative network of life science groups. We offer a multifaceted scientific project with excellent technical facilities, a place in a young, friendly, interactive, and committed team, as well as strong scientific collaborations. Jena is a recognized international center for infectious disease and sepsis research hosting amongst others the Cluster of Excellence “
Balance of the Microverse”, the graduate “
Jena School for Microbial Communication (JSMC)”, the
Center for Sepsis Control and Care, the
German Sepsis Society.
Salary is paid according to German TV-L (salary agreement for public service employees). As an equal opportunity employer, the Leibniz-HKI is committed to increasing the percentage of female scientists and therefore especially encourages them to apply.
Further information:
Prof. Dr. Sebastian Weis | +49 3641 532-1011 | career@leibniz-hki.de
Applications:
Complete applications in English should include a cover letter, a CV containing a complete list of publications, a brief statement of research experiences, and the addresses of two possible referees and should be submitted via the Leibniz-HKI
online application system. The deadline for the advertisement is
March 30, 2024, but applications will be reviewed on a rolling basis.